Promethazine HCl and Codeine Phosphate Oral Option is indicated for your temporary reduction of coughs and upper respiratory signs or symptoms associated with allergy or the frequent chilly in sufferers 18 yrs of age and more mature.

Drug interactions, together with an increased incidence of extrapyramidal consequences, are described when some MAOI and phenothiazines are utilized concomitantly.

Lactation At the least a person Loss of life was documented inside of a nursing toddler who was exposed to high levels of morphine in breast milk as the mother was an ultra-speedy metabolizer of codeine.

The narcotic antagonist, naloxone hydrochloride, could be administered when significant respiratory despair happens with promethazine and codeine; any depressant effects of promethazine are not reversed with naloxone. Diazepam may be made use of to regulate convulsions. Steer clear of analeptics, which can lead to convulsions. Acidosis and electrolyte losses ought to be corrected. A rise in temperature or pulmonary complications may possibly signal the need for institution of antibiotic therapy.

If you're taking promethazine/codeine consistently all through pregnancy, your infant might have withdrawal indications which might be existence-threatening. Tell your Health care service provider in case you took promethazine/codeine in the course of your pregnancy, especially near the finish of your pregnancy.

Promethazine hydrochloride wasn't mutagenic inside the in vitro bacterial reverse mutation assay or clastogenic in the in vitro Chinese here hamster ovary (CHO) cell chromosomal aberration assay.

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The causal position of opioids within the scientific syndrome of hypogonadism is not known since the various health care, Bodily, Way of life, and psychological stressors that will influence more info gonadal hormone concentrations have not been adequately managed for in website scientific tests done up to now [see Adverse Reactions (6)].

There might be other side effects of promethazine/codeine that are not listed listed here. Get in touch with your Health care supplier if you believe you happen to be having a aspect impact of the medication.

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Overdose of codeine in Older people has long been associated with lethal respiratory melancholy, and the use of codeine in kids youthful than 12 years of age is involved with deadly respiratory depression when used as suggested [see Warnings and Safety measures (5.

Narcotic analgesics cross the placental barrier. The nearer to shipping and delivery plus the greater the dose made use of, the greater the potential of respiratory melancholy while in the new child. Narcotic analgesics ought to be averted for the duration of labor if shipping of the untimely infant is predicted.

The decision to reclassify the check here medication continues to be designed following a session with unbiased authorities, Health care experts and clients. 992 responses were acquired.

An anticholinergic drugs, which includes antihistamines and medicines normally useful for overactive bladder, Parkinson’s condition, or Codeine Linctus Cough Syrup tummy challenges